What is DFPP?
DFPP (Double Filtration Plasmapheresis) is a modern, selective blood washing method that removes harmful substances from the plasma while preserving and returning most of the regular blood components to the body. Unlike traditional plasmapheresis, DFPP does not require the administration of donor plasma, which significantly reduces the risk of immunological and infectious complications.
Safety – Facts
- Many years of clinical experience: DFPP has been used in medicine for decades and is considered a particularly safe method of plasmapheresis.
- Advanced safety features: The procedure is performed under medical supervision, using disposable, sterile filtration sets and modern devices equipped with safety sensors (e.g., detecting blood leaks, air in the system, or hemoglobin abnormalities).
- No need for donor plasma: The patient does not receive blood or plasma from other people, whichminimizes the risk of allergic reactions, infections or immunological complications.
- Painless procedure: The procedure is generally painless, and the only discomfort may occur when inserting the IV cannula, as it does during blood drawing.
- No need to stop taking medications: Most medications can be taken during DFPP therapy, but you should always provide your doctor with a full list of substances you take.
- Low risk of complications: The most common side effects are short-term dizziness (related to anticoagulants) and minor discomfort at the injection site.
Risks and possible complications
- Minor discomfort: Slight pain or discomfort at the IV insertion site, similar to a blood draw.
- Short-term dizziness: Caused by anticoagulants, especially after the first treatment. It is recommended that the patient be accompanied by another person for the first treatment.
- Limited physical activity After the procedure, avoid strenuous exercise for 24–48 hours.
- Rare complications: Minimal risk of infection, bleeding, or bruising at the injection site. Serious complications (e.g., severe allergic reactions, severe coagulation disorders) are very rare and mainly affect patients with significant comorbidities.
- Complications related to vascular access: Mostly mild (e.g., catheter site thrombosis), rarely requiring intervention.
Contraindications
- Individual assessment: Before the procedure, the doctor assesses the patient's health and medications. Contraindications include severe coagulation disorders, circulatory instability, active infections, and allergies to anticoagulants.
- No universal contraindications: Most patients can safely use DFPP after appropriate medical qualification.
Myths about DFPP
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Summary
DFPP is a modern, selective, and safe blood washing method used to treat numerous conditions. The risk of complications is low, and most side effects are mild. Serious complications are very rare and mainly affect patients with severe comorbidities. Medical evaluation and adherence to the recommendations of medical personnel are crucial. Most fears and myths about DFPP are not supported by scientific research or clinical practice.
Remember
If you have any doubts or questions about the procedure’s safety consult your doctor!
