Women's Health: Ovarian Regeneration and Fertility – The Role of DFPP
DFPP (Double Filtration Plasmapheresis) is an advanced blood washing method that is also used in treating infertility and its complications. By selectively removing toxic compounds, antibodies, and metabolic waste products, DFPP can significantly improve patient’s health, especially those with chronic complications.
Indications for DFPP in gynecology and infertility treatment:
DFPP helps remove antisperm antibodies that can cause fertilization failure.
A treatment performed before embryo transfer may increase the chance of pregnancy by reducing harmful substances and improving the endometrial environment.
DFPP removes cytokines and immune complexes, reducing inflammation and improving ovarian function.
In cases where autoimmune processes are responsible for the loss of ovarian reserve, DFPP helps limit destructive antibodies.
Reduction of autoantibodies may improve pregnancy outcome and fetal development.
DFPP is used as an adjunct treatment for this complication of ovarian stimulation.
Plasma washing before transfer may reduce the risk of implantation failure or miscarriage.
Mechanism of action
DFPP selectively removes the following substances from plasma:
- Antibodies (e.g. antiphospholipid, antisperm).
- Immune complexes.
- Cytokines and toxins.
- Heavy metals.
Effects:
- Reduced chronic inflammation and immunological burden on the ovaries and reproductive system.
- Better conditions for ovarian regeneration and improvement of their function.
- Increased chances of proper embryo implantation and pregnancy development.
Modern therapy for infertility
- The procedure is safe, performed using modern equipment, without the need for donor blood.
- Basic blood tests and a medical consultation are required before the procedure.
- A typical procedure takes 3-4 hours, and the number of sessions is determined individually.
Summary
DFPP is a promising method for supporting women with fertility problems, especially when the failures are related to autoimmune or inflammatory factors.. It can be helpful both before and during assisted reproductive procedures, as well as in conditions such as premature ovarian failure or endometriosis.
