Stem Cell & DFPP – Patient FAQ | Novacell Clinic

We’ve collected the most frequently asked questions and prepared answers for you. Read on.

Quick, Evidence-Based Answers from an Expert
1. What is stem cell therapy?

Stem cell therapy is a modern treatment method that involves administering cells capable of regenerating and repairing damaged tissue. These cells can come from the body’s own body (autologous) or from a donor (allogeneic). The most commonly used cells are those derived from adipose tissue, umbilical cord blood, or bone marrow.

2. What diseases can be treated with this method?

Therapy is considered in, among others:

  • Urological diseases: stress urinary incontinence (SUI), overactive bladder, neurogenic bladder,
  • Gynecological diseases: infertility, premature ovarian failure,
  • Autoimmune and inflammatory diseases: rheumatoid arthritis, lupus, multiple sclerosis, amyotrophic lateral sclerosis.
  • Neurological diseases: Parkinson’s disease, ALS, stroke rehabilitation, spinal cord injuries, multiple sclerosis.
  • Orthopedic and musculoskeletal diseases: osteoarthritis, tendon and ligament damage, intervertebral disc degeneration, chronic joint pain and inflammation.
  • Cardiovascular and metabolic diseases: chronic heart failure, coronary heart disease, type 2 diabetes (especially complications such as neuropathy or difficult-to-heal wounds).
  • Other chronic conditions: COPD , chronic kidney disease, erectile dysfunction (of vascular origin), difficult-to-heal wounds and ulcers.
  • Aesthetic and regenerative medicine: anti-aging , skin and hair regeneration
  • Other: after individual qualification
3. Is the therapy safe?

Yes, if it’s performed in a reputable clinic, by an experienced team, and using certified products. Each stage of therapy is subject to strict quality control. The most common side effects are mild local symptoms (redness, swelling, pain) that quickly subside. The risk of serious complications is low, but it cannot be completely ruled out .

4. Can everyone benefit from stem cell therapy?

No. Eligibility is determined by a physician after a detailed analysis of the patient’s health status, medical history, and test results. Contraindications include active cancer, uncontrolled infections, severe immunosuppression, unstable chronic illnesses, pregnancy, severe coagulation disorders, and active addictions.

5. What does the treatment process look like?
  • Consultation and qualification: The doctor analyzes medical records, conducts an interview and performs tests.
  • Therapy planning: An individual treatment plan, source and type of cells, and method of administration are determined.
  • Procedure: Cells are administered intravenously or locally. The procedure is minimally invasive and usually does not require hospitalization.
  • Post-procedure care: The patient receives recommendations and remains under the care of the medical team, with follow-up visits.
6. Where do stem cells come from?

The most commonly used are:

  • cord blood cells
  • cells from your own fat tissue (collected during minimally invasive liposuction),
  • bone marrow cells,
7. What are the effects of therapy and when can they be expected?

The effects depend on the type of condition, age, and overall health of the patient. Typically, improved function, reduced pain, and improved quality of life are observed. Initial results may appear after several weeks or months. In some cases, additional treatments or supportive therapies may be necessary.

8. Is the therapy reimbursed?

Most stem cell therapies are not reimbursed because they are innovative or experimental. Costs are determined individually, depending on the scope of treatment.

9. How to prepare for the procedure?

You will receive detailed instructions regarding medication discontinuation, diet, hydration, and laboratory testing. Please bring your medical records and comfortable clothing on the day of your procedure.

10. Can I travel after the procedure?

Most procedures are minimally invasive and allow you to return home the same day. For international patients, the clinic can assist with travel arrangements, transfers, and translations.

11. How long does recovery take?

You can usually return to daily activities after 24–48 hours. Your doctor will advise you on how to limit your exertion and monitor the injection site.

Yes, as long as it is conducted in accordance with applicable laws and international guidelines. At NOVACELL, we use only certified products and adhere to the highest ethical standards.

Patient FAQs on DFPP
1. What is DFPP?

DFPP ( Double Filtration Plasmapheresis is a modern, selective blood purification method in which harmful substances (e.g., antibodies, toxins, immune complexes, lipids) are removed from the patient’s plasma, and most of the healthy components are returned to the body. Unlike classic plasmapheresis, DFPP does not require the administration of plasma from a donor—only the patient’s own blood is used.

2. Who is the DFPP treatment for?

DFPP is used to treat and support the treatment of over 50 different conditions, including autoimmune diseases (MS, RA, SLE, Hashimoto’s), neuropathy, chronic fatigue syndrome, metabolic diseases (e.g., hypercholesterolemia), post-COVID-19, heavy metal poisoning, psoriasis, skin diseases, as well as support before and after in vitro procedures and to improve the body’s overall regeneration.

3. What does the procedure look like?
  • The procedure usually takes 3–4 hours.
  • The patient remains in a comfortable armchair, under the constant supervision of medical staff.
  • Two intravenous lines are placed (in both arms).
  • Blood flows through two filters: the first separates plasma from blood cells, the second selectively removes harmful substances.
  • The purified plasma and blood cells are returned to the body, and the “dirty” plasma is removed.
  • After the procedure, you can benefit from individual IV vitamin therapy.
4. Is the procedure painful?

Aside from a brief discomfort during IV insertion (similar to having blood drawn), the procedure is painless.

5. How to prepare for DFPP?
  • Bring current blood test results: blood count, APTT, PT, INR, WR, HBsAg , anti-HCV, HIV (not older than 3 months).
  • Eat a regular meal before your procedure.
  • Wear comfortable clothing with short sleeves.
  • Bring your ID, snacks, headphones, and a blanket.
  • Please arrive 20 minutes early to complete your paperwork.
6. Can I drive after the procedure?

We recommend having someone with you during your first treatment – some patients may experience brief periods of dizziness.

7. Can I exercise after the procedure?

Strenuous exercise is not recommended for 24–48 hours after the procedure (due to blood thinning medications). Light activities such as walking and housework are permitted.

8. How many treatments are needed?

The number of sessions depends on your health condition and the goals of your therapy – sometimes a single treatment is enough, in other cases, your doctor will recommend a series of treatments.

9. Is DFPP safe?

Yes, DFPP is a procedure with a high safety profile, performed for years in hospital medicine. At NOVACELL, we use only disposable, sterile kits and modern equipment with quality certificates. The entire procedure is performed under the supervision of a physician.

10. Do I receive blood or plasma from a donor during the procedure?

No. DFPP uses only your own blood and plasma – there is no risk of transmitting infectious diseases.

11. What are the possible side effects?

The treatment is well tolerated. Short-term dizziness, fatigue, and rare allergic reactions or local irritation at the injection site are possible. Medical staff will monitor your condition throughout the procedure.

12. What are the benefits of DFPP?
  • Removes toxins, heavy metals, antibodies and immune complexes.
  • Reduces chronic inflammation.
  • Relieves the load on the liver and kidneys.
  • Improves oxygenation and nutrition of cells.
  • Increases energy levels and improves well-being.
  • May support fertility and prepare for in vitro procedures
13. Can DFPP be combined with other therapies?

Yes, DFPP is often used as a pre-treatment for stem cell therapy, exosomes , or other advanced regenerative methods, increasing their effectiveness.

14. Can anyone benefit from DFPP?

No. Eligibility is determined by a physician after analyzing your health, medical history, and test results. Contraindications exist, including severe coagulation disorders, active infections, and certain chronic diseases.

15. What is post-treatment care like?

After the procedure, you will receive personalized recommendations regarding diet, activity, and medication. If you experience any concerning symptoms, you can contact the NOVACELL team. Follow-up visits or teleconsultations are scheduled to monitor the effects of the treatment.

Have any questions?

please contact our team – we'll be happy to answer any questions you may have and help you make an informed decision about stem cell therapy or DFPP.